Twist Bioscience Corp (TWST) Financial Ratio Screen

NASDAQ Healthcare United States USD 8866M
RATIOS FAIL*
Automated financial screen · activity assessed separately
Twist Bioscience Corp (TWST) is potentially non-compliant in the automated ratio model. While the debt ratio of 11.8% is acceptable, the cash and interest-bearing securities ratio of 36.2% exceeds the 30% threshold. Twist Bioscience Corp operates in the Healthcare sector.

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MSCI new-inclusion financial-ratio snapshot

TWST financial screening at a glance

RATIOS FAIL*Financial ratios shown separately from business review — not a fatwa
Debt ratio
11.8%
Pass vs 30%
Cash ratio
36.2%
Fail vs 30%
Receivables + cash
45.1%
Fail vs 30%
Impermissible income
3.0%
Pass vs 5%

Calculation date: 2026-08-31. Financial period used: September 2025. The ratios are automated proxies inspired by published methodologies; they are not official index determinations.

Independent method comparison

What the available screens say

How MSCI, FTSE and S&P-style screens differ
Request this stock review
MSCI-styleFinancial criteria not metAt least one available ratio exceeds its threshold
FTSE/Yasaar-styleFinancial criteria not metAt least one available ratio exceeds its threshold
S&P-style provisionalNot yet availableRequired denominator or financial data is incomplete
Business activityAssessment pendingFinancial results do not determine business permissibility
Complete screening result: not yet completeA complete result requires both supported financial criteria and adequate activity evidence. This site does not issue a fatwa or official index decision.
Financial periodSeptember 2025Calculation date2026-08-31S&P-style historynot availableLast activity reviewnot yet reviewed

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Business activity evidence

Activity assessment in progress

The supplied classification (Diagnostics & Research) is only a starting point. Revenue evidence is being assessed before any complete screening conclusion.

Revenue segments: Not yet checked against an SEC annual filing.

Profile description reviewed: Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. The company offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development. It also provides NGS tools comprising library preparation kits, human exome kits, and fixed and custom panels, as well as alliance panels used within diagnostic tests for various indications, population genetics research and biomarker discovery, translational research, microbiology, and applied markets research; and methylation detection kits for cancer, and rare and inherited disease study, as well as fast hybridization and full RNA sequencing workflow solution. In addition, it offers synthetic SARS-CoV-2 RNA reference sequences as positive controls to develop both NGS and reverse transcription-polymerase chain reaction assays; synthetic monkeypox controls; and various respiratory viral controls, including for influenzas, respiratory syncytial virus, rhinoviruses, SARS, MERS, and coronaviruses. Further, it offers SARS-CoV-2 Research Panels, such as the Twist Respiratory Virus Panel and the Pan-Viral Research Panel, for the detection of disease in a research setting; precision DNA libraries for antibody engineering, affinity maturation, and humanization; and antibody optimization solution to enable simultaneous optimization of multiple characteristics of a given antibody. The company has a strategic collaboration with bitBiome Inc. The company was incorporated in 2013 and is headquartered in South San Francisco, California.

Sources to verify: Secondary company profile and classification · Issuer website · SEC issuer filings

A sector label or company description can flag a risk but cannot establish a compliant-revenue percentage. Only sourced segment disclosures may support that calculation.

Published-ratio reproductions (not certifications)

The table shows implemented MSCI and FTSE/Yasaar-style asset-based models plus a provisional S&P-style leverage reconstruction where a complete 36-month denominator exists. These are independent calculations, not official index results or Shariah determinations. See formulas, sources and limitations.

Based on financial data from September 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
MSCI 11.8%
/ 30%
36.2%
/ 30%
45.1%
/ 30%
3.02%
/ 5%
RATIOS FAIL*
FTSE 11.8%
/ 33%
36.2%
/ 33%
45.1%
/ 50%
3.02%
/ 5%
RATIOS FAIL*

Financial Highlights

EPS
$-2.06
P/B Ratio
19.9
EV/EBITDA
-76.4
EV: $8.8B
Revenue
$377M
Growth: 23.2%
Beta
2.2
High volatility
Current Ratio
2.7

Profitability

Gross Margin 52.0%
Operating Margin -30.6%
Net Margin -31.7%
Return on Equity (ROE) -29.6%
Return on Assets (ROA) -13.1%

Cash Flow & Balance Sheet

Operating Cash Flow-$48M
Free Cash Flow-$76M
Total Debt$76M
Debt-to-Equity24.4
Current Ratio2.7
Total Assets$642M

Price & Trading

Last Close$153.10
50-Day MA$106.72
200-Day MA$62.21
Avg Volume1.8M
Beta2.2
52-Week Range
$23.30
$155.44

Financial data provenance and verification

The displayed fields were imported from yfinance on 2026-08-30 for the financial period September 2025. This is a secondary data feed and can differ from amended or newly filed statements.

Verification rule: check debt, cash, receivables, revenue and interest income against the latest primary filing before relying on an automated ratio.

About Twist Bioscience Corp (TWST)

CEO
Dr. Emily Marine Leproust Ph.D.
Employees
979
Sector
Healthcare
Industry
Diagnostics & Research
Country
United States
Exchange
NASDAQ
Market Cap (listing currency)
USD 8866M
Currency
USD

Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. The company offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development. It also provides NGS tools comprising library preparation kits, human exome kits, and fixed and custom panels, as well as alliance panels used within diagnostic tests for various indications, population genetics research and biomarker discovery, translational research, microbiology, and applied markets research; and methylation detection kits for cancer, and rare and inherited disease study, as well as fast hybridization and full RNA sequencing workflow solution. In addition, it offers synthetic SARS-CoV-2 RNA reference sequences as positive controls to develop both NGS and reverse transcription-polymerase chain reaction assays; synthetic monkeypox controls; and various respiratory viral controls, including for influenzas, respiratory syncytial virus, rhinoviruses, SARS, MERS, and coronaviruses. Further, it offers SARS-CoV-2 Research Panels, such as the Twist Respiratory Virus Panel and the Pan-Viral Research Panel, for the detection of disease in a research setting; precision DNA libraries for antibody engineering, affinity maturation, and humanization; and antibody optimization solution to enable simultaneous optimization of multiple characteristics of a given antibody. The company has a strategic collaboration with bitBiome Inc. The company was incorporated in 2013 and is headquartered in South San Francisco, California.

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Frequently Asked Questions

Is Twist Bioscience Corp (TWST) halal to invest in?

The current automated result is Financial criteria not met or an activity exclusion was detected. It uses available public financial fields and simplified methodology proxies. It is not a fatwa or an official determination by AAOIFI, DJIM, MSCI, S&P, or FTSE.

What is Twist Bioscience Corp's debt ratio?

Twist Bioscience Corp's debt ratio is 11.8% in the MSCI new-inclusion reproduction: total debt divided by total assets, against a 30% threshold. See the methodology page for the official source and limitations.

What are Twist Bioscience Corp's key financial metrics?

Twist Bioscience Corp has a market capitalization of USD 8866M in its listing currency, and revenue of $377M. The company maintains a gross margin of 52.0% and a net margin of -31.7%. Return on equity stands at -29.6%.

How often is the screening data updated?

Calculation date: 2026-08-31. Financial period: September 2025. These dates are shown separately because regenerating this page does not refresh the underlying data.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.