Taysha Gene Therapies, Inc. (TSHA) Financial Ratio Screen

NASDAQ Healthcare United States USD 1463M
RATIOS FAIL*
Automated financial screen · activity assessed separately
Taysha Gene Therapies, Inc. (TSHA) is potentially non-compliant in the automated ratio model. While the debt ratio of 20.4% is acceptable, the cash and interest-bearing securities ratio of 93.1% exceeds the 30% threshold. Taysha Gene Therapies, Inc. operates in the Healthcare sector.

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MSCI new-inclusion financial-ratio snapshot

TSHA financial screening at a glance

RATIOS FAIL*Financial ratios shown separately from business review — not a fatwa
Debt ratio
20.4%
Pass vs 30%
Cash ratio
93.1%
Fail vs 30%
Receivables + cash
N/A
Not available vs 30%
Impermissible income
94.4%
Fail vs 5%

Calculation date: 2026-10-15. Financial period used: December 2025. The ratios are automated proxies inspired by published methodologies; they are not official index determinations.

Independent method comparison

What the available screens say

How MSCI, FTSE and S&P-style screens differ
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MSCI-styleFinancial criteria not metAt least one available ratio exceeds its threshold
FTSE/Yasaar-styleFinancial criteria not metAt least one available ratio exceeds its threshold
S&P-style provisionalNot yet availableRequired denominator or financial data is incomplete
Business activityAssessment pendingFinancial results do not determine business permissibility
Complete screening result: not yet completeA complete result requires both supported financial criteria and adequate activity evidence. This site does not issue a fatwa or official index decision.
Financial periodDecember 2025Calculation date2026-10-15S&P-style historynot availableLast activity reviewnot yet reviewed

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Business activity evidence

Activity assessment in progress

The supplied classification (Biotechnology) is only a starting point. Revenue evidence is being assessed before any complete screening conclusion.

Revenue segments: Not yet checked against an SEC annual filing.

Profile description reviewed: Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

Sources to verify: Secondary company profile and classification · Issuer website · SEC issuer filings

A sector label or company description can flag a risk but cannot establish a compliant-revenue percentage. Only sourced segment disclosures may support that calculation.

Published-ratio reproductions (not certifications)

The table shows implemented MSCI and FTSE/Yasaar-style asset-based models plus a provisional S&P-style debt and cash reconstruction where a complete 36-month denominator exists. These are independent calculations, not official index results or Shariah determinations. See formulas, sources and limitations.

Based on financial data from December 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
MSCI 20.4%
/ 30%
93.1%
/ 30%
N/A 94.38%
/ 5%
RATIOS FAIL*
FTSE 20.4%
/ 33%
93.1%
/ 33%
N/A 94.38%
/ 5%
RATIOS FAIL*

Financial Highlights

EPS
currency unverified -0.41
Dividend Yield
0.0%
P/B Ratio
6.1
EV/EBITDA
-7.0
EV: USD 1.1B
Revenue
USD 10M
Beta
1.2
Average volatility
Current Ratio
17.8

Profitability

Gross Margin 100.0%
Operating Margin -2792.3%
Net Margin 0.0%
Return on Equity (ROE) -47.1%
Return on Assets (ROA) -23.8%

Cash Flow & Balance Sheet

Operating Cash FlowUSD -93M
Free Cash FlowUSD -94M
Total DebtUSD 70M
Debt-to-Equity14.6
Current Ratio17.8
Total AssetsUSD 343M

Price & Trading

Last Close$4.63
50-Day MA$5.62
200-Day MA$5.46
Avg Volume3.2M
Beta1.2
52-Week Range
$3.69
$7.30

Financial data provenance and verification

The displayed fields were imported from yfinance on 2026-10-06 for the financial period December 2025. This is a secondary data feed and can differ from amended or newly filed statements.

Verification rule: check debt, cash, receivables, revenue and interest income against the latest primary filing before relying on an automated ratio.

About Taysha Gene Therapies, Inc. (TSHA)

CEO
Mr. Sean P. Nolan
Employees
99
Sector
Healthcare
Industry
Biotechnology
Country
United States
Exchange
NASDAQ
Market Cap (listing currency)
USD 1463M
Currency
USD

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

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Frequently Asked Questions

Is Taysha Gene Therapies, Inc. (TSHA) halal to invest in?

The current automated result is Financial criteria not met or an activity exclusion was detected. It uses available public financial fields and simplified methodology proxies. It is not a fatwa or an official determination by AAOIFI, DJIM, MSCI, S&P, or FTSE.

What is Taysha Gene Therapies, Inc.'s debt ratio?

Taysha Gene Therapies, Inc.'s debt ratio is 20.4% in the MSCI new-inclusion reproduction: total debt divided by total assets, against a 30% threshold. See the methodology page for the official source and limitations.

What are Taysha Gene Therapies, Inc.'s key financial metrics?

Taysha Gene Therapies, Inc. has a market capitalization of USD 1463M in its listing currency, and revenue of USD 10M. Return on equity stands at -47.1%.

How often is the screening data updated?

Calculation date: 2026-10-15. Financial period: December 2025. These dates are shown separately because regenerating this page does not refresh the underlying data.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.