Stoke Therapeutics, Inc. (STOK) Financial Ratio Screen

NASDAQ Healthcare United States USD 1816M
RATIOS FAIL*
Automated financial screen · activity assessed separately
Stoke Therapeutics, Inc. (STOK) is potentially non-compliant in the automated ratio model. While the debt ratio of 0.7% is acceptable, the cash and interest-bearing securities ratio of 68.0% exceeds the 30% threshold. Stoke Therapeutics, Inc. operates in the Healthcare sector.

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MSCI new-inclusion financial-ratio snapshot

STOK financial screening at a glance

RATIOS FAIL*Financial ratios shown separately from business review — not a fatwa
Debt ratio
0.7%
Pass vs 30%
Cash ratio
68.0%
Fail vs 30%
Receivables + cash
22.0%
Pass vs 30%
Impermissible income
N/A
Not available vs 5%

Calculation date: 2026-10-15. Financial period used: December 2025. The ratios are automated proxies inspired by published methodologies; they are not official index determinations.

Independent method comparison

What the available screens say

How MSCI, FTSE and S&P-style screens differ
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MSCI-styleFinancial criteria not metAt least one available ratio exceeds its threshold
FTSE/Yasaar-styleFinancial criteria not metAt least one available ratio exceeds its threshold
S&P-style provisionalNot yet availableRequired denominator or financial data is incomplete
Business activityAssessment pendingFinancial results do not determine business permissibility
Complete screening result: not yet completeA complete result requires both supported financial criteria and adequate activity evidence. This site does not issue a fatwa or official index decision.
Financial periodDecember 2025Calculation date2026-10-15S&P-style historynot availableLast activity reviewnot yet reviewed

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Business activity evidence

Activity assessment in progress

The supplied classification (Biotechnology) is only a starting point. Revenue evidence is being assessed before any complete screening conclusion.

Revenue segments: Not yet checked against an SEC annual filing.

Profile description reviewed: Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy; and Zorevunersen (STK-001), an investigational new medicine for the treatment of Dravet syndrome is being evaluated in phase 3 clinical trials. The company also develops programs focused on various targets, including haploinsufficiency diseases of the central nervous system and eye. It has a license and collaboration with Biogen Inc. for the development and commercialization of zorevunersen medicine for the treatment of Dravet syndrome; and Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of genetic neurodevelopmental diseases. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

Sources to verify: Secondary company profile and classification · Issuer website · SEC issuer filings

A sector label or company description can flag a risk but cannot establish a compliant-revenue percentage. Only sourced segment disclosures may support that calculation.

Published-ratio reproductions (not certifications)

The table shows implemented MSCI and FTSE/Yasaar-style asset-based models plus a provisional S&P-style debt and cash reconstruction where a complete 36-month denominator exists. These are independent calculations, not official index results or Shariah determinations. See formulas, sources and limitations.

Based on financial data from December 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
MSCI 0.7%
/ 30%
68.0%
/ 30%
22.0%
/ 30%
N/A RATIOS FAIL*
FTSE 0.7%
/ 33%
68.0%
/ 33%
22.0%
/ 50%
N/A RATIOS FAIL*

Financial Highlights

EPS
currency unverified -3.23
P/B Ratio
5.1
EV/EBITDA
-6.9
EV: 1.5B (currency unverified)
Revenue
184M (currency unverified)
Growth: -32.5%
Beta
1.2
High volatility
Current Ratio
7.7

Profitability

Gross Margin 100.0%
Operating Margin -701.7%
Net Margin 0.0%
Return on Equity (ROE) -61.1%
Return on Assets (ROA) -35.9%

Cash Flow & Balance Sheet

Operating Cash Flow46M (currency unverified)
Free Cash Flow45M (currency unverified)
Total Debt3M (currency unverified)
Debt-to-Equity0.8
Current Ratio7.7
Total Assets418M (currency unverified)

Price & Trading

Last Close$29.60
50-Day MA$30.87
200-Day MA$31.98
Avg Volume893K
Beta1.2
52-Week Range
$20.32
$40.22

Financial data provenance and verification

The displayed fields were imported from yfinance on 2026-09-16 for the financial period December 2025. This is a secondary data feed and can differ from amended or newly filed statements.

Verification rule: check debt, cash, receivables, revenue and interest income against the latest primary filing before relying on an automated ratio.

About Stoke Therapeutics, Inc. (STOK)

CEO
Mr. Ian F. Smith A.C.A., C.P.A.
Employees
170
Sector
Healthcare
Industry
Biotechnology
Country
United States
Exchange
NASDAQ
Market Cap (listing currency)
USD 1816M
Currency
USD

Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy; and Zorevunersen (STK-001), an investigational new medicine for the treatment of Dravet syndrome is being evaluated in phase 3 clinical trials. The company also develops programs focused on various targets, including haploinsufficiency diseases of the central nervous system and eye. It has a license and collaboration with Biogen Inc. for the development and commercialization of zorevunersen medicine for the treatment of Dravet syndrome; and Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of genetic neurodevelopmental diseases. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

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Frequently Asked Questions

Is Stoke Therapeutics, Inc. (STOK) halal to invest in?

The current automated result is Financial criteria not met or an activity exclusion was detected. It uses available public financial fields and simplified methodology proxies. It is not a fatwa or an official determination by AAOIFI, DJIM, MSCI, S&P, or FTSE.

What is Stoke Therapeutics, Inc.'s debt ratio?

Stoke Therapeutics, Inc.'s debt ratio is 0.7% in the MSCI new-inclusion reproduction: total debt divided by total assets, against a 30% threshold. See the methodology page for the official source and limitations.

What are Stoke Therapeutics, Inc.'s key financial metrics?

Stoke Therapeutics, Inc. has a market capitalization of USD 1816M in its listing currency, and revenue of 184M (currency unverified). Return on equity stands at -61.1%.

How often is the screening data updated?

Calculation date: 2026-10-15. Financial period: December 2025. These dates are shown separately because regenerating this page does not refresh the underlying data.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.