Is Sionna Therapeutics, Inc. (SION) Halal?

NASDAQ Healthcare United States $1.6B
✓ HALAL
Confidence: 83/100
Sionna Therapeutics, Inc. (SION) is Halal under 3 of 5 Shariah screening standards, including AAOIFI Standard 21. With a debt ratio of just 0.6% against the AAOIFI threshold of 30%, Sionna Therapeutics, Inc. comfortably passes the key financial ratio tests. The company operates in the Healthcare sector (Biotechnology), which is not a prohibited industry under Islamic finance principles.

Shariah Screening — 5 Standards

Based on financial data from December 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
AAOIFI 0.6%
/ 30%
9.2%
/ 30%
0.0%
/ 30%
N/A ✓ HALAL
DJIM 0.6%
/ 33%
9.2%
/ 33%
0.0%
/ 33%
N/A ✓ HALAL
MSCI 5.2%
/ 33%
79.4%
/ 33%
0.0%
/ 33%
N/A ✗ NOT HALAL
S&P 0.6%
/ 33%
9.2%
/ 33%
0.0%
/ 33%
N/A ✓ HALAL
FTSE 5.2%
/ 33%
79.4%
/ 33%
0.0%
/ 50%
N/A ✗ NOT HALAL

Financial Highlights

EPS
$-1.88
P/B Ratio
5.3
EV/EBITDA
-15.8
EV: $1.4B
Revenue
$0
Current Ratio
20.6

Profitability

Gross Margin 0.0%
Operating Margin 0.0%
Net Margin 0.0%
Return on Equity (ROE) -31.8%
Return on Assets (ROA) -21.7%

Cash Flow & Balance Sheet

Operating Cash Flow-$66M
Free Cash Flow-$67M
Total Debt$9M
Debt-to-Equity2.8
Current Ratio20.6
Total Assets$326M

Price & Trading

Last Close$37.96
50-Day MA$38.01
200-Day MA$31.36
Avg Volume280K
52-Week Range
$7.25
$45.00

About Sionna Therapeutics, Inc. (SION)

CEO
Mr. Michael Cloonan M.B.A.
Employees
59
Sector
Healthcare
Industry
Biotechnology
Country
United States
Exchange
NASDAQ
Market Cap
$1.6B
Currency
USD

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial. The company was formerly known as Sling Therapeutics, Inc. and changed its name to Sionna Therapeutics, Inc. in July 2021. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

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Frequently Asked Questions

Is Sionna Therapeutics, Inc. (SION) halal to invest in?

Based on our screening using AAOIFI Standard 21 (the strictest methodology), Sionna Therapeutics, Inc. is Halal. The company passes all financial ratio thresholds for debt, cash, receivables, and impermissible income. We screen against all 5 major standards: AAOIFI, DJIM, MSCI, S&P, and FTSE.

What is Sionna Therapeutics, Inc.'s debt ratio?

Sionna Therapeutics, Inc.'s debt ratio is 0.6% under the AAOIFI standard (which uses market capitalization as the denominator). The AAOIFI threshold is 30%. Under MSCI and FTSE (which use total assets as the denominator), the debt ratio is 5.2%.

What are Sionna Therapeutics, Inc.'s key financial metrics?

Sionna Therapeutics, Inc. has a market capitalization of $1.6B. Return on equity stands at -31.8%.

How often is the screening data updated?

Our screening data is updated regularly using the latest available financial statements and market data. Stock prices and market caps are refreshed frequently, while financial statements are updated quarterly when companies report earnings.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.