PUMA BIOTECHNOLOGY, INC. (PBYI) Financial Ratio Screen

NASDAQ Healthcare United States USD 309M
RATIOS FAIL*
Automated financial screen · activity assessed separately
PUMA BIOTECHNOLOGY, INC. (PBYI) is potentially non-compliant in the automated ratio model. While the debt ratio of 13.2% is acceptable, the cash and interest-bearing securities ratio of 45.1% exceeds the 30% threshold. PUMA BIOTECHNOLOGY, INC. operates in the Healthcare sector.

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MSCI new-inclusion financial-ratio snapshot

PBYI financial screening at a glance

RATIOS FAIL*Financial ratios shown separately from business review — not a fatwa
Debt ratio
13.2%
Pass vs 30%
Cash ratio
45.1%
Fail vs 30%
Receivables + cash
69.9%
Fail vs 30%
Impermissible income
1.8%
Pass vs 5%

Calculation date: 2026-09-01. Financial period used: December 2025. The ratios are automated proxies inspired by published methodologies; they are not official index determinations.

Independent method comparison

What the available screens say

How MSCI, FTSE and S&P-style screens differ
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MSCI-styleFinancial criteria not metAt least one available ratio exceeds its threshold
FTSE/Yasaar-styleFinancial criteria not metAt least one available ratio exceeds its threshold
S&P-style provisionalNot yet availableRequired denominator or financial data is incomplete
Business activityAssessment pendingFinancial results do not determine business permissibility
Complete screening result: not yet completeA complete result requires both supported financial criteria and adequate activity evidence. This site does not issue a fatwa or official index decision.
Financial periodDecember 2025Calculation date2026-09-01S&P-style historynot availableLast activity reviewnot yet reviewed

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Business activity evidence

Activity assessment in progress

The supplied classification (Biotechnology) is only a starting point. Revenue evidence is being assessed before any complete screening conclusion.

Revenue segments: Not yet checked against an SEC annual filing.

Profile description reviewed: Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. It sells its products through specialty pharmacy and distributor networks. The company has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Puma Biotechnology, Inc. was founded in 2010 and is headquartered in Los Angeles, California.

Sources to verify: Secondary company profile and classification · Issuer website · SEC issuer filings

A sector label or company description can flag a risk but cannot establish a compliant-revenue percentage. Only sourced segment disclosures may support that calculation.

Published-ratio reproductions (not certifications)

The table shows implemented MSCI and FTSE/Yasaar-style asset-based models plus a provisional S&P-style leverage reconstruction where a complete 36-month denominator exists. These are independent calculations, not official index results or Shariah determinations. See formulas, sources and limitations.

Based on financial data from December 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
MSCI 13.2%
/ 30%
45.1%
/ 30%
69.9%
/ 30%
1.79%
/ 5%
RATIOS FAIL*
FTSE 13.2%
/ 33%
45.1%
/ 33%
69.9%
/ 50%
1.79%
/ 5%
RATIOS FAIL*

Financial Highlights

P/E Ratio
10.0
Forward: 9.4
EPS
$0.61
P/B Ratio
2.4
EV/EBITDA
5.1
EV: $240M
Revenue
$228M
Growth: 27.7%
Beta
1.3
High volatility
Current Ratio
2.0

Profitability

Gross Margin 74.5%
Operating Margin 22.7%
Net Margin 13.6%
Return on Equity (ROE) 28.0%
Return on Assets (ROA) 10.9%

Cash Flow & Balance Sheet

Operating Cash Flow$42M
Free Cash Flow$42M
Total Debt$29M
Debt-to-Equity21.9
Current Ratio2.0
Total Assets$216M

Price & Trading

Last Close$6.27
50-Day MA$6.52
200-Day MA$5.18
Avg Volume425K
Beta1.3
52-Week Range
$2.58
$7.68

Financial data provenance and verification

The displayed fields were imported from yfinance on 2026-03-29 for the financial period December 2025. This is a secondary data feed and can differ from amended or newly filed statements.

Verification rule: check debt, cash, receivables, revenue and interest income against the latest primary filing before relying on an automated ratio.

About PUMA BIOTECHNOLOGY, INC. (PBYI)

CEO
Mr. Alan H. Auerbach
Employees
179
Sector
Healthcare
Industry
Biotechnology
Country
United States
Exchange
NASDAQ
Market Cap (listing currency)
USD 309M
Currency
USD

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. It sells its products through specialty pharmacy and distributor networks. The company has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Puma Biotechnology, Inc. was founded in 2010 and is headquartered in Los Angeles, California.

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Frequently Asked Questions

Is PUMA BIOTECHNOLOGY, INC. (PBYI) halal to invest in?

The current automated result is Financial criteria not met or an activity exclusion was detected. It uses available public financial fields and simplified methodology proxies. It is not a fatwa or an official determination by AAOIFI, DJIM, MSCI, S&P, or FTSE.

What is PUMA BIOTECHNOLOGY, INC.'s debt ratio?

PUMA BIOTECHNOLOGY, INC.'s debt ratio is 13.2% in the MSCI new-inclusion reproduction: total debt divided by total assets, against a 30% threshold. See the methodology page for the official source and limitations.

What are PUMA BIOTECHNOLOGY, INC.'s key financial metrics?

PUMA BIOTECHNOLOGY, INC. has a market capitalization of USD 309M in its listing currency, trailing P/E ratio of 10.0, and revenue of $228M. The company maintains a gross margin of 74.5% and a net margin of 13.6%. Return on equity stands at 28.0%.

How often is the screening data updated?

Calculation date: 2026-09-01. Financial period: December 2025. These dates are shown separately because regenerating this page does not refresh the underlying data.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.