Orchestra BioMed Holdings, Inc. (OBIO) Financial Ratio Screen

NASDAQ Healthcare United States USD 344M
RATIOS FAIL*
Automated financial screen · activity assessed separately
Orchestra BioMed Holdings, Inc. (OBIO) is potentially non-compliant in the automated ratio model. While the debt ratio of 13.9% is acceptable, the cash and interest-bearing securities ratio of 92.7% exceeds the 30% threshold. Orchestra BioMed Holdings, Inc. operates in the Healthcare sector.

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MSCI new-inclusion financial-ratio snapshot

OBIO financial screening at a glance

RATIOS FAIL*Financial ratios shown separately from business review — not a fatwa
Debt ratio
13.9%
Pass vs 30%
Cash ratio
92.7%
Fail vs 30%
Receivables + cash
30.3%
Fail vs 30%
Impermissible income
N/A
Not available vs 5%

Calculation date: 2026-10-17. Financial period used: December 2025. The ratios are automated proxies inspired by published methodologies; they are not official index determinations.

Independent method comparison

What the available screens say

How MSCI, FTSE and S&P-style screens differ
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MSCI-styleFinancial criteria not metAt least one available ratio exceeds its threshold
FTSE/Yasaar-styleFinancial criteria not metAt least one available ratio exceeds its threshold
S&P-style provisionalNot yet availableRequired denominator or financial data is incomplete
Business activityAssessment pendingFinancial results do not determine business permissibility
Complete screening result: not yet completeA complete result requires both supported financial criteria and adequate activity evidence. This site does not issue a fatwa or official index decision.
Financial periodDecember 2025Calculation date2026-10-17S&P-style historynot availableLast activity reviewnot yet reviewed

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Business activity evidence

Activity assessment in progress

The supplied classification (Biotechnology) is only a starting point. Revenue evidence is being assessed before any complete screening conclusion.

Revenue segments: Not yet checked against an SEC annual filing.

Profile description reviewed: Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a bioelectronic product candidate that aims to reduce chronic sympathetic nervous system activity in heart failure. In addition, the company offers FreeHold devices and additional minimally invasive surgery enabling devices; and Pure-Vu system, a medical device to facilitate the cleansing of a poorly prepared gastrointestinal tract during colonoscopy and upper gastrointestinal endoscopy procedures. It has a collaboration agreement with Medtronic, Inc. for the development of AVIM therapy for the treatment of HTN in pacemaker-indicated patients; and a strategic collaboration with Terumo Corporation and Terumo Medical Corporation for the development and commercialization of Virtue SAB for the treatment of coronary and peripheral vascular disease. Orchestra BioMed Holdings, Inc. was founded in 2018 and is headquartered in New Hope, Pennsylvania.

Sources to verify: Secondary company profile and classification · Issuer website · SEC issuer filings

A sector label or company description can flag a risk but cannot establish a compliant-revenue percentage. Only sourced segment disclosures may support that calculation.

Published-ratio reproductions (not certifications)

The table shows implemented MSCI and FTSE/Yasaar-style asset-based models plus a provisional S&P-style debt and cash reconstruction where a complete 36-month denominator exists. These are independent calculations, not official index results or Shariah determinations. See formulas, sources and limitations.

Based on financial data from December 2025

Standard Debt Ratio Cash Ratio Receivables Income Status
MSCI 13.9%
/ 30%
92.7%
/ 30%
30.3%
/ 30%
N/A RATIOS FAIL*
FTSE 13.9%
/ 33%
92.7%
/ 33%
30.3%
/ 50%
N/A RATIOS FAIL*

Financial Highlights

EPS
currency unverified -0.86
Dividend Yield
0.0%
P/B Ratio
17.8
EV/EBITDA
-5.5
EV: USD 315M
Revenue
USD 33M
Growth: -89.5%
Beta
0.5
Low volatility
Current Ratio
8.3

Profitability

Gross Margin 99.5%
Operating Margin -25404.5%
Net Margin -184.6%
Return on Equity (ROE) -397.3%
Return on Assets (ROA) -45.7%

Cash Flow & Balance Sheet

Operating Cash FlowUSD -49M
Free Cash FlowUSD -49M
Total DebtUSD 16M
Debt-to-Equity240.5
Current Ratio8.3
Total AssetsUSD 115M

Price & Trading

Last Close$5.91
50-Day MA$5.39
200-Day MA$4.44
Avg Volume300K
Beta0.5
52-Week Range
$3.26
$6.50

Financial data provenance and verification

The displayed fields were imported from yfinance on 2026-10-14 for the financial period December 2025. This is a secondary data feed and can differ from amended or newly filed statements.

Verification rule: check debt, cash, receivables, revenue and interest income against the latest primary filing before relying on an automated ratio.

About Orchestra BioMed Holdings, Inc. (OBIO)

CEO
Mr. David P. Hochman
Employees
86
Sector
Healthcare
Industry
Biotechnology
Country
United States
Exchange
NASDAQ
Market Cap (listing currency)
USD 344M
Currency
USD

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a bioelectronic product candidate that aims to reduce chronic sympathetic nervous system activity in heart failure. In addition, the company offers FreeHold devices and additional minimally invasive surgery enabling devices; and Pure-Vu system, a medical device to facilitate the cleansing of a poorly prepared gastrointestinal tract during colonoscopy and upper gastrointestinal endoscopy procedures. It has a collaboration agreement with Medtronic, Inc. for the development of AVIM therapy for the treatment of HTN in pacemaker-indicated patients; and a strategic collaboration with Terumo Corporation and Terumo Medical Corporation for the development and commercialization of Virtue SAB for the treatment of coronary and peripheral vascular disease. Orchestra BioMed Holdings, Inc. was founded in 2018 and is headquartered in New Hope, Pennsylvania.

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Frequently Asked Questions

Is Orchestra BioMed Holdings, Inc. (OBIO) halal to invest in?

The current automated result is Financial criteria not met or an activity exclusion was detected. It uses available public financial fields and simplified methodology proxies. It is not a fatwa or an official determination by AAOIFI, DJIM, MSCI, S&P, or FTSE.

What is Orchestra BioMed Holdings, Inc.'s debt ratio?

Orchestra BioMed Holdings, Inc.'s debt ratio is 13.9% in the MSCI new-inclusion reproduction: total debt divided by total assets, against a 30% threshold. See the methodology page for the official source and limitations.

What are Orchestra BioMed Holdings, Inc.'s key financial metrics?

Orchestra BioMed Holdings, Inc. has a market capitalization of USD 344M in its listing currency, and revenue of USD 33M. The company maintains a gross margin of 99.5% and a net margin of -184.6%. Return on equity stands at -397.3%.

How often is the screening data updated?

Calculation date: 2026-10-17. Financial period: December 2025. These dates are shown separately because regenerating this page does not refresh the underlying data.

Disclaimer: HalalStockGuide.com provides Shariah compliance screening for educational and informational purposes only. This is not a fatwa, financial advice, or a recommendation to buy or sell any security. Screening results are based on publicly available financial data and established methodologies. Always consult a qualified Islamic scholar and a licensed financial advisor before making investment decisions.